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GLP-1 Receptor Agonists [review]

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Previous studies have shown that the Taq1A polymorphism is linked to obesity-related outcomes in children, where individuals with polymorphisms that have decreased basal dopaminergic signaling could potentially be at risk for increased psychiatric side effects following GLP-1RA administration [159]

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Notably, neuromodulatory effects elicited by the microbiome are largely dependent on vagal signaling (Bravo et al., 2011