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Concurrently, GLP-1 stimulates the translocation of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) into the nucleus via the PKA/ERK signaling pathway, where Nrf2 induces transcription of genes for SOD, GPx, catalase, thioredoxin, and other antioxidant enzymes, further enhancing the cellular antioxidant defense system

This is due to its ability to regulate blood sugar, reduce appetite, and slow digestion, resulting in weight loss as a common side effect

1L) and DPP4 on days 35 and 42 (Fig

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I 2 50%), analyses were performed using the MantelHaenszel method and fixed-effects models

But small human studies suggest that yerba mate, or green mate (which contains the same active compound), may help with fat loss and appetite reduction