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doi: 10.1124/jpet.118.255885 136 RadyBLiuJHuangHBakajIQiJLeeSPet al

According to the RLS Foundation, one in ten American adults suffer from restless legs syndrome (RLS), a neurological condition characterized by the irresistible impulse (often described as a "creeping" or "itching" feeling) to move one's legs

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For now, it serves as a reminder that healthcare is not one-size-fits-all, and even small adjustments may have significant impacts

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[6] [7] These gastrointestinal effects result from the medications' impact on gastric motility and are generally most pronounced during dose escalation, often improving with continued therapy as tolerance develops