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Am J Physiol 1993;265(4 Pt 1):L374L381

adults over age 20 meet the criteria for obesity, according to the Centers for Disease Control and Prevention

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17 In the central nervous system, insulin contributes to synaptic maintenance, neuron growth and survival, as well as maintenance and regulation of learning and memory 18

This happens because the medication suppresses appetite while it is being used, but it does not permanently change the underlying biological drivers of weight regain

The researchers speculated that EMPA could cross through a compromised BBB and exert neuroprotective benefits