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Gut Microbiome Dysbiosis, Inflammation, and Systemic Risk Subsequently, gut microbiome dysbiosis has been associated with metabolic dysfunction, poor mental health, chronic disease, cardiovascular disease (CVD), reduced longevity, neurodegeneration, and inflammation

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As recently reported, these symptoms were significantly higher in diabetic patients treated with high-dose of GLP-1 RAs compared to dipeptidyl peptidase 4 inhibitors [54]

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The label itself makes an important admission: it hasnt been established that appetite suppression is its only effect in obesity, because it also produces other central nervous system actions