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In the SYNERGY-NASH trial, a phase 2 study involving participants with metabolic dysfunctionassociated steatohepatitis (MASH) and moderate or severe fibrosis, treatment with tirzepatide for 52 weeks was more effective than placebo in achieving resolution of MASH without worsening fibrosis [146]
Obesity is a growing epidemic that affects millions of people worldwide, leading to serious health complications such as heart disease, diabetes, and certain cancers
2022;119(13, article e2116506119) doi: 10.1073/pnas.2116506119
The increasing investments and collaborations also contribute to market growth
2024;386:e079475
The first GLP-1 receptor agonist approved by the FDA was exenatide in 2005, derived directly from the lizard venom compound
