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At the same time, new clinical findings show semaglutide may actually reduce alcohol cravings and drinking behavior in those with alcohol use disorder

It is important to note that the optimal dosage of Wegovy (semaglutide) for weight loss may vary among individuals

SELECT Trial The SELECT trial, one of the largest cardiovascular outcomes trials in obesity medicine, enrolled over 17,000 participants with established cardiovascular disease and obesity or overweight (without diabetes) and demonstrated a 20% reduction in MACE with semaglutide 2.4 mg

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Additionally, the recent development of an orally available preparation of semaglutide (Rybelsus , Novo Nordisk), and the recruitment of GLP-1 into unimolecular pharmacology with GIP, glucagon (and others) (88) exemplifies how GLP-1-based drug development and innovation advanced over recent years

Evidence-Based Care Built on the strongest obesity-medicine evidence of the last decade