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This GPCR is primarily expressed in the pancreas by -cells, -cells and -cells (271, 318, 319), and is found at lower concentrations along the GI tract, especially in the stomach and duodenum, where counterintuitively only a minor fraction of CCK, and GLP-1 expressing duodenal enteroendocrine cells display GPR119 (266, 271)

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Most patients spend less on food while on treatment

Without eating disorder screening, a prescriber may see a patient in a higher-weight body and recommend a GLP-1 medication without any awareness that they are treating someone in the midst of a life-threatening restrictive illness

While 5-Amino-1MQ shows promise in preclinical studies and research, it is important to note that further investigation is needed to fully understand its mechanisms of action, safety profile, and potential applications in human health, particularly in relation to weight loss and managing excess weight