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While effective, these treatments require monitoring due to potential side effects, especially in non-diabetic patients.This therapeutic advancement represents a revolution in the management of metabolic diseases and obesity.Despite their efficacy in managing obesity and metabolic disorders, GLP-1 and GIP receptor agonists can cause side effects, which are a common reason for therapy discontinuation

Appetite suppression can make it easy to eat too little protein, increasing the risk of muscle loss during weight loss

While GLP-1 medications are highly effective, their side effects can present obstacles

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The article explores how medications like semaglutide and tirzepatide, originally approved for diabetes and obesity, are increasingly being prescribed off-label to address underlying metabolic issues such as insulin resistance, weight gain, and hormonal []