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Oral formulations not only have advantages of convenience over injectables but also bypasses the need for the cold chain , and the need to secure a large supply of injectable pens which the majority of off-patent companies do not manufacture in-house

Although use of glucagon-like peptide-1 agonists for diabetes and weight loss has soared with indications now expanding into liver diseases, specifically metabolic dysfunction-associated steatohepatitis, the jury is still out on its benefit.With the recent FDA approval of Rezdiffra (resmetirom, Madrigal Pharmaceuticals) for the treatment for MASH, the question is whether (and how) GLP-1s will fit