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Glucagon-like Peptide-1 Potentiates Glucose-stimulated Insulin Secretion via the Transient Receptor Potential Melastatin 2 Channel

[DOI] [PMC free article] [PubMed] [Google Scholar] 159.Reshef L., Olswang Y., Cassuto H., Blum B., Croniger C.M., Kalhan S.C., Tilghman S.M., Hanson R.W

ER stress refers to the activation of ER responses, such as the unfolded protein response (UPR) and apoptosis signaling pathway, through the accumulation of misfolded and unfolded proteins and the disorder of calcium balance after various stress agents are applied to cells
Mounjaro is a medication approved for adults with type 2 diabetes and should be used with diet and exercise

Sci Transl Med 9(404):eaan0972 Mitchell JL et al (2023) The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

Thus, GLP-1 can improve responses to neuroinflammation, and controls the production of cytokines in the brain
