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The fibrotic effects of TMAO on human renal fibroblasts is mediated by NLRP3, caspase-1 and the PERK/Akt/mTOR pathway

Follow the recommendation of a nutritionally informed physician if needed

Schematic timeline of events (g) with onset of the rash on day 0 (d 0)

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In this study, it was suggested that a reduction in TMAO concentration with the use of metformin is an effective therapeutic strategy to exert cardiovascular benefits