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When dehydration reduces blood volume, kidney filtration decreases, urine becomes concentrated, and the risk of both kidney injury and urinary infection increases simultaneously

(2006) 291:E112430

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2021;18(3):e1003583

And none of the big GLP-1 trials studied anything like microdosing

In Phase III studies under the Harmony program, patients treated with albiglutide showed statistically significant reductions in HbA1c compared to placebo
