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Clinical data shows significant improvements in eating behavior within weeks of starting treatment

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The molecule contains a modified amino acid sequence derived from the glucagon backbone and includes substitutions designed to improve resistance to enzymatic degradation while preserving receptor binding functionality

On November 14, 2025, Scholar Rock released its third-quarter financial and pipeline update, announcing that it had held a constructive, face-to-face Type A meeting with the FDA regarding the BLA for its core asset, Apitegromab, intended for the treatment of spinal muscular atrophy (SMA) in both children and adults

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