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In SUSTAIN-6, a small increase in SBP (+1.9 mm Hg) was observed among Black participants receiving the 0.5 mg dose of semaglutide, although this subgroup was small ( n = 54) and the effect was not seen at the 1.0 mg dose

Low ferritin, vitamin B12, folate, or magnesium reserves amplify energy depletion during rapid weight loss

Reflections on the Discovery GLP-1 as a Satiety Hormone: Implications for Obesity Therapy and Future Directions

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GLP-1 RA suppresses appetite and food reward to elicit rapid weight loss
Those who have not developed new habits to manage this increased hunger are more likely to rebound
