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Others are approved for type 2 diabetes and may lead to weight loss as a secondary effect

Additionally, GLP-1 appears to promote neurogenesis and enhance synaptic plasticity in the hippocampus, a brain region critical for memory formation that is particularly vulnerable in Alzheimer's disease

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SGLT2-i induced natriuresis and glomerular hemodynamics changes resemble, even partially, those observed with sacubitril/valsartan, a first in-class angiotensin receptor neprilysin inhibitor (ARNi)

doi: 10.1016/S0140-6736(23)01291-6 [DOI] [PubMed] [Google Scholar] 82