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Adding the probiotic to a broader metabolic support protocol that includes targeted nutrition changes, regular exercise, and adequate sleep may be necessary to create the cumulative effect that the probiotic alone cannot deliver

7: e462

Retrieved from Institute of Medicine

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Finally, one can foresee a future where combination therapy becomes common: for example, a patient with diabetes and obesity might be on both a GLP-1 RA and an SGLT2 inhibitor (for complementary weight loss and cardio-renal protection, which is already done)

It is also for patients who are already considering GLP-1 therapy and want to understand how liver health should fit into the medical weight loss conversation