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adults (12%) say that they have taken a GLP-1 drug, and 6% that say they are currently taking such medications

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An absolute standardised difference of 65 and 65 years) and sex

This can be challenging because many people need to stay on weight loss medications to maintain a lower body weight, and some medications take weeks to work

Whether or not initial up-titration has to be recommended for a given compound/preparation depends on these agents pharmacokinetic properties

More recently, dual GIP/GLP-1 RAs, such as tirzepatide, as well as emerging dual and triple incretin-based therapies, have demonstrated substantial efficacy in both glycaemic and weight control