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Recent evidence from the STEP-HFpEF and STEP-HFpEF-DM trials provides the first robust data supporting the efficacy of GLP-1 RAs, specifically semaglutide, in improving the quality of life in obese patients with HFpEF

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Nicola Magrini, Unit head for Innovation, Evidence synthesis and Clinical research, University Hospital, Bologna, Italy, Co-Chair of the Guidelines Development GroupComments: GLP-1 and inclusion in the essential medicineMr Deus Mubangizi, Director, Medicines and Health Products Policies and Standards Department, WHOPanel discussionMs Jeanette Hunter General Primary Health Care at the National Department of Health (NDoH) of South Africa, and Co-Chair of the Guidelines Development Group

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Supporting natural GLP-1 activity can make a significant difference in energy levels, weight management, and overall wellness

Microglial glucagon-like peptide-1 receptor (GLP-1R) activation can alleviate pain