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Injection site reactions are localized skin responses that can occur where the medication is injected typically the abdomen, thigh, or upper arm

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McCulloch AJ, Johnston DG, Baylis PH, Kendall-Taylor P, Clark F, Young ET, et al

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For weekly semaglutide, steady state is generally achieved after 4 to 5 weeks of consistent dosing, while liraglutide reaches steady state within 3 to 5 days due to its shorter half-life (approximately 13 hours)