glp-1 and microbiome Effects of receptor agonist on changes in the gut bacterium the underlying mechanisms Crosstalk between GLP-1 and the

Then came the duals (like #tirzepatide), and even triagonists (#retatrutide) that pushed weight loss even farther

And now

You did it

A new GLP-1 oral medication from AstraZeneca, known as elecoglipron, lowered blood sugar levels and led to 10.5% weight loss in a phase 2b clinical trial.

GLP-1, or glucagon-like peptide-1, is a hormone produced in the gut in response to eating

Embrace the Chill (The Energy Burn) This one may feel uncomfortable, but short bursts of cold exposure (like a 30-second cold shower finish) dont just wake you up, they stimulate your Brown Fat (BAT).Brown fats job is to burn calories for heat, and its activation improves overall metabolic health and insulin sensitivity.While the connection is indirect, research suggests that this major metabolic wake-up call creates an environment that supports the healthy function and release of critical signalling hormones like GLP-1, helping to optimise your body's energy balance