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GLP-1R plays a critical role in the signaling cascades leading to insulin release in response to an increase in blood glucose levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Arai Y, Martin-Ruiz C M, Takayama M, Abe Y, Takebayashi T, Koyasu S et al

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a few percent develop high titers which might reduce efficacy ( [105] ) ( [108] )

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Clinical evidence of antidepressant effects of insulin and anti-hyperglycemic agents and implications for the pathophysiology of depressiona literature review