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Both medications share a similar side effect profile because both activate the GLP-1 receptor

Nevertheless, the exact mechanism by which GLP-1 analogues promote IL-6 expression in monocytes is still unclear

Better safety profile : Serious side effects were less common in people taking liraglutide (7%) compared to those getting placebo (18%)

Manufacturers must strike a delicate balance between access, value perception, and sustaining profitability in the context of reimbursement constraints

While semaglutide is generally well tolerated, it is most commonly associated with gastrointestinal symptoms such as nausea or diarrhea, especially during the early stages of treatment or when the dose is increased