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In the proximal small intestine, L cells also express considerable amounts of GIP, cholecystokinin (CCK), and secretin
The mechanistic processes that link diabetes and cancer are not completely understood
The authors hypothesize that this paradoxical worsening is due to a cytokine imbalance, similar to what is seen with the exacerbation of disease after administration of biological treatments like anti-TNF, which increases interferon (IFN)- release and leukocyte chemotaxis [25]
