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Zepbound (tirzepatide) weekly injection dosing schedule The weekly dosing schedule of Zepboud is as follows: Weeks 1-4 (starting dose): 2.5 mg once weekly for the first 4 weeks Weeks 5-8: 5 mg once weekly Weeks 9-12: 7.5 mg once weekly Weeks 13-16 : If tolerated, increase to 10 mg once weekly Weeks 17-20: If the dosage needs to be escalated further, increase to 12.5 mg once weekly for 4 weeks Weeks 21 and onward : If the previous dose is ineffective, the next dose will be 15 mg once weekly

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GLP-1 Market Trends and Global Forecasts Report 2025: A $157.5 Bn Market by 2035 - Landscape Led by China and the U.S., Rising Partnerships, and Strong DTC-Driven Demand Push Biologics Above 65% Share The GLP-1 market is primed for substantial growth due to rising obesity and diabetes rates

62 Different ligands lead to different interaction patterns with the receptor, generating various effects

Employers and health plans alike must consider strategies, such as leveraging integrated data, to ensure appropriate utilization and prevent unnecessary spend

M.et al (2024)