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This comparative perspective juxtaposes the two compounds with respect to molecular pharmacology, clinical efficacy, safety, and potential clinical positioning, and proposes that, because resmetirom primarily targets hepatic lipid disposal whereas semaglutide unloads systemic caloric pressure, their complementary actions could be harnessed sequentially or in combination to achieve broader, more durable disease modification across the heterogeneous spectrum of patients with MASH

Gradual tapering may be recommended to minimize side effects

Clinically-Proven Weight Loss Medication Ozempic works by mimicing the GLP-1 receptors in the body to lower appetite and blood sugar levels

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If someone is experiencing great results on Trulicity, switching to Ozempic may not be beneficial