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Dulaglutide reduces binge episodes in type 2 diabetic patients with BED: a pilot study

GMA105 is a fusion protein that combines GLP-1 fragments with a humanized monoclonal antibody against GLP-1R, while GMA106 includes an antagonistic GIPR antibody fused with GLP-1 molecules, achieving dual receptor activation

This does not indicate treatment failure

This comprehensive review assesses the contemporary state of bariatric surgery and systematically examines the clinical efficacy, safety, and durability of emerging pharmacotherapies relative to surgical interventions

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It encompasses trials SURPASS from 1 to 6 ( Figure 3A ), SURPASS-J (mono and combo) and SURPASS-AP, performed respectively on Japanese and Asian-Pacific population ( Figure 3B ), and SURPASS CVOT