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However, adverse events, particularly nausea and digestive symptoms, were more common among participants taking GLP-1 drugs, and some stopped treatment due to side effects

So instead of lowering blood sugar, it raises glucose levels when they become too low

Investigation into GLP-1-based diabetes therapies concluded

Short-acting GLP-1 agonists like exenatide (taken twice daily) may produce more immediate effects on post-meal glucose levels, whilst longer-acting weekly formulations such as semaglutide or dulaglutide provide more sustained action but may take longer to reach steady-state concentrations in the body

"Not all GLP-1s are the same

GLP-1 receptor agonists mimic natural incretin hormones that regulate appetite, satiety, and glucose metabolism through actions on the brain, pancreas, and gastrointestinal tract