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Holst JJ, Rosenkilde MM

animal studies suggest extremely high doses cause GI toxicity rather than systemic organ failure

Nausea is typically mild to moderate and is often most noticeable when first starting the medication or increasing the dose

But if you are dealing with severe or long-standing obesity, that is a starting point, not a finish line

Glucagon receptor activation in adipose tissue and the liver stimulates energy expenditure, increases fat oxidation, and promotes lipolysis

My goal has never been weight loss
