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324 Inhibition of the lncRNA MIR4435-2HG regulates macrophage M1/M2 polarization through the JAK1/STAT1 pathway, thus alleviating intestinal inflammation and colon injury

Nature Reviews Endocrinology , 17(12), 757769

doi: 10.1055/s-0029-1210974 34 VilaGJoergensenJOLLugerAStallaGK

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In an animal model, daily GIP injections decreased proinflammatory cytokines (IL-6, interleukin-1, and TNF- ) while increasing lipocalin levels [40], while GLP-1 receptor activation upregulates the second messenger cyclic adenosine monophosphate (cAMP) and activates protein kinase A (PKA)

Liraglutide: short-lived effect on gastric emptying - long lasting effects on body weight
