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Notably, studies have shown that GLP-1 RA therapy can reverse the iNKT cell ratio in psoriatic lesions and circulation, leading to a reduction in the number of these cells within plaques and an increase in their presence in peripheral blood [56]

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N Engl J Med 2021;384:1113-24.ArticlePubMed 120

Glucagon-like peptide-1 (GLP-1)-based therapies, which regulate blood glucose and body weight, show sex-specific effects, with estradiol potentiating their metabolic benefits

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