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dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

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A., Kemmeries, G., Holst, J

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

JAMA Neurol 76:10881098

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

doi: 10.1186/s10020-024-00817-8, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 92

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

doi:10.1038/nm727 321

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

Liraglutide (Victoza, Saxenda) : Approved for type 2 diabetes (1.8 mg daily) and chronic weight management (3.0 mg daily)

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

82 For patients with obesity and HFpEF, GLP-1 RAs, such as semaglutide, are safe, with fewer serious cardiovascular events reported

dual agonist glp 1 glucagon Machine learning designs new GCGR/GLP-1R agonists with enhanced biological potency Polyagonists Enable Increasingly Effective Treatment

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