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These medications are changing the way obesity and weight management are approached, by controlling appetite and food intake

190 In general, cyanopyrrolidines such as saxagliptin are competitive inhibitors rather than noncompetitive inhibitors of DPP-IV enzymatic activity since they form reversible covalent bonds with serine residue 630 located within the enzyme's active site

2020 Jul;37(7):120

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(NIDDK) Blood sugar becomes more stable, which can reduce the drive to eat in response to large metabolic swings

In postmenopause, there may also be an increased risk for certain health conditions like urinary tract infections (UTIs), heart disease, and osteoporosis due to decreased estrogen in the body