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Retatrutide should be considered a second-line or specialized first-line agent for complex cases once it gains regulatory approval
You get 90% of the weight loss efficacy of the 12mg dose but with noticeably fewer side effects during the challenging weeks 6-8 period
doi: 10.1210/endrev/bnaa032
doi: 10.1016/j.bcp.2024.116119
H., Anis, A
Some researchers keep their remaining tirzepatide as a safety net during the early weeks of retatrutide transition
