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[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Zhang L., Pitcher L.E., Yousefzadeh M.J., Niedernhofer L.J., Robbins P.D., Zhu Y

Elevated cAMP acts mainly through the following molecular pathways: inhibition of the ERK pathway, activation of the PKA-AMPK-mTOR pathway, and activation of the p38 signaling pathway [13, 17, 56,57,58]: first, it inhibits the extracellular signal-regulated kinase (ERK) pathway, decreasing its activation of cyclin D1, thereby hindering cyclin D1-mediated DNA replication initiation and transition into the S phase of the cell cycle [17]

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[DOI] [Google Scholar] 52.Sotornik R., Brassard P., Martin E., Yale P., Carpentier A

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