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3 Wegovy pill is also indicated to reduce the risk of major adverse cardiovascular events (MACE) such as death, heart attack, or stroke in adults with overweight or obesity and established cardiovascular disease

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The SELECT trial further showed that once-weekly semaglutide reduced first-event MACE by 20% in adults with obesity and prior cerebrovascular disease, extending cardiovascular protection beyond diabetes [319, 320]

10.1016/j.lfs.2011.12.001 143
