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However, the two classes of agents differ largely in their pharmacological modes of action on glucose-lowering and CV parameters
75% of Americans are considered to be overweight, but that number is starting to drop because of popular weight-loss injections.
Nevertheless, bone consequences of intentional weight loss interventions in PwO are well known: (i) significant weight loss induced by caloric restriction and bariatric surgery results in accelerated bone turnover and bone loss, and (ii) unlike caloric restriction interventions, PwO experience a substantial deterioration in bone microarchitecture and strength associated with an increased risk of fracture after bariatric surgery especially malabsorptive procedures
