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You've likely heard the buzz about GLP-1s

Most Americans believe being healthy and fit is one of the current status symbols particularly shared by Millennials

Michigan's largest health insurer, Blue Cross Blue Shield of Michigan, is stopping coverage for glucagon-like peptide-1 (GLP-1) drugs used for weight loss starting in January 2025

Since tirzepatide is a dual GLP1R/GIPR agonist, the interpretation is compelling: GIP receptor activation normally buffers the nausea-inducing effects of GLP-1 agonism, and when that buffer is genetically impaired, the GLP-1 component goes unchecked

Serious adverse events reported in temporal association with GLP-1 RA exposure included anaphylaxis with bronchospasm (n=4 cases), acute eosinophilic pneumonia (n=1), perioperative aspiration pneumonitis or pneumonia (multiple perioperative cases across two cohort studies and one case series), acute respiratory distress syndrome (ARDS

Novo Nordisk has turned to pricing as a means to shore up its position in the increasingly competitive market for GLP-1 agonist therapies in the US.