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Expected BMI reduction of 10 % at a dose of 15 mg/92 mg for 56 weeks

GEP44 group, n = 8) were provided with a high-fat (HF) diet (60% cal from fat, 5.21 kcal/g) for 20 weeks before the start of the study

Program of Shanghai Academic/Technology Research Leader (23XD1400900 to D.Y.) and Shanghai Sailing Program (22YF1457200 to F.Z.)

2019;7:e000705

French physiologist Jean La Barre first used the term incretine in 1932 to describe a substance which lowered glucose levels by augmenting insulin release and actions.4 5 We now know that GLP-1 and glucose-dependent insulinotropic peptide (GIP) are the two main incretin hormones