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[DOI] [PubMed] [Google Scholar] 39.Packer M

The high molecular weight of both liraglutide and semaglutide would theoretically prevent them from crossing placenta

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The Journal of Endocrinology

However, various observational studies have shown that metformin may even lead to a reduction in mortality in patients with heart failure [60], so according to current understanding, metformin can be considered a safe drug for patients with diabetes and heart failure

Dosing depends on the specific medication
