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The safest patient-friendly answer is: possibly, in selected patientsespecially those with existing diabetic retinopathy, especially early after starting treatment, and especially when glucose improves rapidly

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2025) showed that combining semaglutide with GDF8/activin A blockers preserved lean mass and enhanced fat loss in preclinical models

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2 Clinical Effect of SGLT2 Inhibitors The efficacy and safety of SGLT2 inhibitors have been extensively investigated, especially in combination with metformin and/or other glucose-lowering drugs in T2D patients

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