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To put it in context, lifestyle interventions typically achieve 20-30% liver fat reduction, while semaglutide produces approximately 40-50% reduction in comparable studies

The study enrolled 83 male patients with obesity and metabolic hypogonadism (mean age, 55.3 years

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Dose-response relationship in clinical trials The SURMOUNT clinical trial program tested tirzepatide at 5 mg, 10 mg, and 15 mg weekly doses