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Eli Lillys next-generation obesity drug Retatrutide achieved 28.3% average weight loss in a pivotal Phase 3 trial, with nearly 45% of patients losing

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Longitudinal Targeted Minimum Loss-based Estimation, a method that adjusts for both baseline and time-varying confounding, was used to estimate absolute risks of cardiovascular outcomes under sustained use of GLP1-RA and DPP 4i (active comparator), adjusting for baseline and time-varying confounding

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