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Shares of Eli Lilly climbed about 4% on Monday after the drugmaker unveiled encouraging new clinical data for its next-generation obesity treatment, retatrutide

Therefore, ox-LDLs through LOX-1 are responsible for several downstream effects, including endothelial activation with increased expression of adhesion molecules, monocyte recruitment with macrophage differentiation and foam cell formation, apoptosis, smooth muscle cell proliferation and migration, platelet activation, extracellular matrix deposition, and fibroatheroma formation [11]