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Furthermore, activation of the GLP-1R inhibits vascular smooth muscle cell proliferation (10)

Freemark M, Bursey D

However, it is uncertain whether those actions directly contribute to the nephroprotective effects of GLP-1 receptor agonists

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doi: 10.1016/j.npep.2010.02.002
Small variations in chemical structure, as well as different dosage and delivery methods, may affect how they are approved for use