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While regulatory bodies and pharmaceutical companies are discussing potential solutions to the drug shortages, societies such as the American Diabetes Association are providing guidelines to assist with alternative treatment options for patients with type 2 diabetes mellitus as well as guidelines to assist with dosage changes to be made while GLP-1 therapies are low in stock

A robust pipeline of oral GLP-1 agents and next-generation therapies with complementary mechanisms is advancing swiftly, intensifying competition and expanding future treatment possibilities

Retatrutide is undergoing clinical trials and is not yet licensed in the UK, online services that are offering this are not safe and should be considered a risk

Ozempics packaging also warns of more potentially severe side effects such as pancreatitis, changes in vision, kidney failure and the possibility of developing thyroid tumors

On one hand, GLP-1RA could reduce the proliferation of effector T cells, promote the generation and function of Treg cells