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Brown, D

Patients typically notice itching within 30 minutes to 2 hours after injection, with peak intensity occurring between 26 hours

Ultraviolet radiation can directly break peptide bonds and trigger oxidation reactions independent of temperature

The medication may become less predictable due to reduced sterility and potential degradation, which could affect treatment results

This includes daily inspection of the skin for cuts, blisters, redness, or signs of infection, particularly on the feet

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