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Domain 2: Detailed explanation of sample size calculation

[DOI] [PubMed] [Google Scholar] 38.Antidepressants and body weight: a comprehensive review and meta-analysis

Pre-Approval Clinical Trial Data The clinical trials that led to FDA approval showed: High rates of nausea, vomiting, and abdominal pain among participants Documented cases of severe gastrointestinal issues requiring medical treatment Evidence that slowed gastric emptying persisted in some patients Reports of adverse event reports related to digestive system paralysis Despite this significant evidence from clinical trials, Novo Nordisks labeling focused on common, temporary side effects while failing to warn patients about the risk of permanent gastroparesis

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Para facilitar o entendimento, a hemoglobina glicada um exame que indica como os nveis de acar no sangue se comportaram ao longo dos ltimos 3 meses
