glp 1 agonist moa Mechanisms of GLP-1 Receptor Agonist-Induced Weight Loss: A Review of Central and Peripheral Pathways in Appetite and Energy Regulation Mechanisms of Action and Therapeutic
Description
Entry Version: Citation: Pancreapedia: Exocrine Pancreas Knowledge Base , DOI: 10.3998/panc.2021.06 Abstract: Glucagon like peptide-1 (GLP-1) is a GI hormone produced in endocrine cells in the distal small intestine by alternative processing of the proglucagon gene product
Academy of Nutrition and Dietetics
Although reported data from trials and real-world series do not show definitive differences between GLP-1 RAs in terms of tolerability (Table 1), there are studies claiming that the tolerability profile may vary between different compounds [1,33,39]
Due to their various modes of action, which include vasodilation, natriuresis, glucose and weight control, and direct cardioprotective effects, GLP-1 receptor agonists have therapeutic potential for treatment of heart failure (41)
Bioorg Med Chem
10.1016/S2213-8587(19)30249-9 45 LamC
