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Patients with preserved beta-cell function and insulin secretion capacity tend to respond better to incretin-based therapies

Schirra J, Wank U, Arnold R, Goke B, Katschinski M

It remains in clinical trials and is still undergoing rigorous research and safety testing

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Elashoff found an elevated risk of pancreatitis and pancreatic cancer (PC) associated with treatment with DPP-4 inhibitor sitagliptin or GLP-1RA Exenatide compared to other medications by assessing the reported adverse events in the Food and Drug Administration (FDA) database

GIPR: gastric inhibitory polypeptide receptor